POST-EJACULATORY INHIBITION OF FEMALE SEXUAL DRIVE VIA HETEROGENEOUS NEURONAL ENSEMBLES IN THE MEDIAL PREOPTIC AREA

Post-ejaculatory inhibition of female sexual drive via heterogeneous neuronal ensembles in the medial preoptic area

Male ejaculation acutely suppresses sexual motivation in male mice.In contrast, relatively little is known about how male ejaculation affects sexual motivation and sexual behavior in female mice.How the brain responds to the completion of mating is also unclear.Here, by using a self-paced mating assay, we first demonstrate that female mice show dec

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Selective RNAi silencing of Schwann cell Piezo1 alleviates mechanical hypersensitization following peripheral nerve injury

The present study was designed to investigate the role of Schwann cell (SC) Piezo1 in peripheral nociception.We first developed an AAV vector Vanity that has primary SC tropism after delivery into the sciatic (or tibial) nerve.This was achieved by packing AAV-GFP transcribed by a CBA promoter using a capsid AAVolig001 to generate AAVolig001-CBA-GFP

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